Let’s Take On PH1, Together

Learn more about primary hyperoxaluria (PH1), signs & symptoms, and living with this rare condition.

About PH1

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Welcome to Take On PH1, a site dedicated to educating the primary hyperoxaluria type 1 (PH1) community.

Although rare, PH1 can affect people of all ages. If it does, we have resources for you.

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Kidney stones are common in people with primary hyperoxaluria type 1 (PH1)

The most common symptom of PH1 is kidney stones that form due to oxalate overproduction in the liver.

The impact of PH1 goes beyond stones

This overproduction of oxalate can damage your kidneys, affecting their ability to filter waste from your blood.

PH1 tends to get worse over time

Because oxalate is constantly overproduced, it may continuously be doing damage, even when you don’t realize it.

About PH1

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Management matters

Your doctor will work with you to develop a management plan to try to reduce symptoms and try to prevent the disease from getting worse. With personalized management, you may find ways to be active and engaged.

Managing PH1

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I draw strength from the community
when it comes to knowing that there are others
out there dealing with the same thing.

Laura W.

Mom of a child with PH1

Living with PH1

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Expand your circle of support

Explore resources and materials designed specifically for the PH1 community.

EXPLORE PH1 RESOURCES

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For those who care

If you are caring for someone living with PH1, we care how you make it work. See the support that can help.

Parents & CAREGIVERS